Investigations on the Transfer of Quinolizidine Alkaloids from Lupinus angustifolius into the Milk of Dairy Cows

Lupin varieties  with a low content of quinolizidine alkaloids (QAs) like blue sweet lupin (BSL) have long been used as a protein source for dairy cows. A health concern for humans may arise from the transfer of acute toxic QAs from feed into cow’s milk. This study is the first to quantify the transfer of QAs from BSL into cow’s milk with experimental and modeling methods. A toxicological assessment of milk containing QAs as measured in this study indicated a potential health concern

The article is published in the Journal of Agricultural and Food Chemistry.

Investigations on the Transfer of Quinolizidine Alkaloids from Lupinus angustifolius into the Milk of Dairy Cows
Anna Maria Engel, Fenja Klevenhusen, Jan-Louis Moenning, Jorge Numata, Carola Fischer-Tenhagen, Benjamin Sachse, Bernd Schäfer, Hildburg Fry, Oliver Kappenstein, and Robert Pieper
Journal of Agricultural and Food Chemistry Article ASAP
DOI: 10.1021/acs.jafc.2c02517


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